AT1A2_HUMAN

Source: hRBCD ; ID: IPI00003021
PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: ATP1A2 , KIAA0778
Protein names and data: AT1A2_HUMAN , Sodium/potassium-transporting ATPase subunit alpha-2; Na(+)/K(+) ATPase alpha-2 subunit; 3.6.3.9 , Sodium pump subunit alpha-2; Flags: Precursor Lenght: 1020 a.a.
Mass: 112265 Da
fasta formatted sequence

Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients.
Catalytic activity: ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).
Disease:
Cellular location: Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Genetic variants

Database cross-references

UniProt: P50993
Ensembl: ENST00000361216
MIM: 104290
MIM: 182340
MIM: 602481
neXtProt: NX_P50993
Antibodypedia: P50993 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.