AT2B1_HUMAN

Source: hRBCD ; ID: IPI00021695
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: ATP2B1 , PMCA1
Protein names and data: AT2B1_HUMAN , Plasma membrane calcium-transporting ATPase 1; PMCA1; 3.6.3.8 , Plasma membrane calcium ATPase isoform 1; Plasma membrane calcium pump isoform 1 Lenght: 1258 a.a.
Mass: 138755 Da
fasta formatted sequence
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Catalytic activity: ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
Cellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Isoform B is ubiquitously expressed. Isoform C is found in brain cortex, skeletal muscle and heart muscle. Isoform D has only been found in fetal skeletal muscle. Isoform K has been found in small intestine and liver.

Genetic variants

Database cross-references

UniProt: P20020
Ensembl: ENST00000261173
Ensembl: ENST00000348959
Ensembl: ENST00000359142
Ensembl: ENST00000428670
MIM: 108731
neXtProt: NX_P20020
Antibodypedia: P20020 (may not find the protein thus also not any antibody)
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