AT2B2_HUMAN

Source: PM23856902
PM22954596
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: ATP2B2 , PMCA2
Protein names and data: AT2B2_HUMAN , Plasma membrane calcium-transporting ATPase 2; PMCA2; 3.6.3.8 , Plasma membrane calcium ATPase isoform 2; Plasma membrane calcium pump isoform 2 Lenght: 1243 a.a.
Mass: 136876 Da
fasta formatted sequence
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Catalytic activity: ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
Cellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Mainly expressed in brain cortex. Found in low levels in skeletal muscle, heart muscle, stomach, liver, kidney and lung. Isoforms containing segment B are found in brain cortex and at low levels in other tissues. Isoforms containing segments X and W are found at low levels in all tissues. Isoforms containing segment A and segment Z are found at low levels in skeletal muscle and heart muscle.

Database cross-references

UniProt: Q01814
Ensembl: ENST00000343816
Ensembl: ENST00000352432
Ensembl: ENST00000360273
Ensembl: ENST00000383800
Ensembl: ENST00000397077
Ensembl: ENST00000460129
MIM: 108733
neXtProt: NX_Q01814
Antibodypedia: Q01814 (may not find the protein thus also not any antibody)
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