AT2B4_HUMAN

Source: hRBCD ; ID: IPI00012490
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: ATP2B4 , ATP2B2, MXRA1
Protein names and data: AT2B4_HUMAN , Plasma membrane calcium-transporting ATPase 4; PMCA4; 3.6.3.8 , Matrix-remodeling-associated protein 1; Plasma membrane calcium ATPase isoform 4; Plasma membrane calcium pump isoform 4 Lenght: 1241 a.a.
Mass: 137920 Da
fasta formatted sequence
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Catalytic activity: ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
Cellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Isoform XB is the most abundant isoform and is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach and brain cortex.

Database cross-references

UniProt: P23634
Ensembl: ENST00000341360
Ensembl: ENST00000357681
Ensembl: ENST00000367218
Ensembl: ENST00000367219
Ensembl: ENST00000391954
MIM: 108732
neXtProt: NX_P23634
Antibodypedia: P23634 (may not find the protein thus also not any antibody)
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