ATPO_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ATP5O , ATPO
Protein names and data: ATPO_HUMAN , ATP synthase subunit O, mitochondrial , Oligomycin sensitivity conferral protein; OSCP; Flags: Precursor Lenght: 213 a.a.
Mass: 23277 Da
fasta formatted sequence
Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
Cellular location: Mitochondrion (By similarity). Mitochondrion inner membrane (By similarity).

Genetic variants

Database cross-references

UniProt: P48047
Ensembl: ENST00000290299
MIM: 600828
neXtProt: NX_P48047
Antibodypedia: P48047 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.