BCCIP_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: BCCIP , TOK1
Protein names and data: BCCIP_HUMAN , BRCA2 and CDKN1A-interacting protein , P21- and CDK-associated protein 1; Protein TOK-1 Lenght: 314 a.a.
Mass: 35979 Da
fasta formatted sequence

Function: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
Cellular location: Nucleus. Note=Colocalizes with BRCA2 in discrete nuclear foci.
Tissue specificity: Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.

Genetic variants

Database cross-references

UniProt: Q9P287
Ensembl: ENST00000278100
Ensembl: ENST00000299130
Ensembl: ENST00000368759
MIM: 611883
neXtProt: NX_Q9P287
Antibodypedia: Q9P287 (may not find the protein thus also not any antibody)
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