C1QB_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: C1QB
Protein names and data: C1QB_HUMAN , Complement C1q subcomponent subunit B; Flags: Precursor Lenght: 253 a.a.
Mass: 26722 Da
fasta formatted sequence

Function: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Disease:
Cellular location: Secreted.

Genetic variants

Database cross-references

UniProt: P02746
Ensembl: ENST00000314933
MIM: 120570
MIM: 613652
neXtProt: NX_P02746
Antibodypedia: P02746 (may not find the protein thus also not any antibody)
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