C2CD5_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: C2CD5 , CDP138, KIAA0528
Protein names and data: C2CD5_HUMAN , C2 domain-containing protein 5 , C2 domain-containing phosphoprotein of 138 kDa Lenght: 1000 a.a.
Mass: 110447 Da
fasta formatted sequence
Function: Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
Cellular location: Cytoplasmic vesicle membrane. Cytoplasm, cell cortex. Cell membrane. Cell projection, ruffle. Note=Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.

Database cross-references

UniProt: Q86YS7
Ensembl: ENST00000333957
Ensembl: ENST00000396028
neXtProt: NX_Q86YS7
Antibodypedia: Q86YS7 (may not find the protein thus also not any antibody)
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