CALU_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CALU
Protein names and data: CALU_HUMAN , Calumenin , Crocalbin; IEF SSP 9302; Flags: Precursor Lenght: 315 a.a.
Mass: 37107 Da
fasta formatted sequence
Function: Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).
Cellular location: Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen (By similarity). Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue specificity: Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.

Genetic variants

Database cross-references

UniProt: O43852
Ensembl: ENST00000249364
Ensembl: ENST00000449187
Ensembl: ENST00000479257
Ensembl: ENST00000535011
Ensembl: ENST00000535623
Ensembl: ENST00000538546
Ensembl: ENST00000542996
MIM: 603420
neXtProt: NX_O43852
Antibodypedia: O43852 (may not find the protein thus also not any antibody)
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