CAN1_HUMAN

Source: hRBCD ; ID: IPI00011285
PM19886704
PM23856902
PM22954596
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: CAPN1 , CANPL1 , PIG30
Protein names and data: CAN1_HUMAN , Calpain-1 catalytic subunit; 3.4.22.52 , Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; Calpain-1 large subunit; Cell proliferation-inducing gene 30 protein; Micromolar-calpain; muCANP Lenght: 714 a.a.
Mass: 81890 Da
fasta formatted sequence
Function: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Catalytic activity: Broad endopeptidase specificity.
Cellular location: Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: P07384
Ensembl: ENST00000279247
Ensembl: ENST00000524773
Ensembl: ENST00000527323
Ensembl: ENST00000533129
Ensembl: ENST00000533820
MIM: 114220
neXtProt: NX_P07384
Antibodypedia: P07384 (may not find the protein thus also not any antibody)
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