CAN2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CAPN2 , CANPL2
Protein names and data: CAN2_HUMAN , Calpain-2 catalytic subunit; 3.4.22.53 , Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpain; Flags: Precursor Lenght: 700 a.a.
Mass: 79995 Da
fasta formatted sequence
Function: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Catalytic activity: Broad endopeptidase specificity.
Cellular location: Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: P17655
Ensembl: ENST00000295006
Ensembl: ENST00000433674
MIM: 114230
neXtProt: NX_P17655
Antibodypedia: P17655 (may not find the protein thus also not any antibody)
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