CBX3_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CBX3
Protein names and data: CBX3_HUMAN , Chromobox protein homolog 3 , HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein Lenght: 183 a.a.
Mass: 20811 Da
fasta formatted sequence
Function: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Cellular location: Nucleus (Potential). Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential).

Database cross-references

UniProt: Q13185
Ensembl: ENST00000337620
Ensembl: ENST00000396386
MIM: 604477
neXtProt: NX_Q13185
Antibodypedia: Q13185 (may not find the protein thus also not any antibody)
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