CCDB1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CCNDBP1 , DIP1, GCIP, HHM
Protein names and data: CCDB1_HUMAN , Cyclin-D1-binding protein 1 , Grap2 and cyclin-D-interacting protein; Human homolog of Maid Lenght: 360 a.a.
Mass: 40262 Da
fasta formatted sequence
Function: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription.
Cellular location: Cytoplasm. Nucleus.
Tissue specificity: Ubiquitously expressed. Expression is down- regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.

Database cross-references

UniProt: O95273
Ensembl: ENST00000300213
Ensembl: ENST00000565296
Ensembl: ENST00000566515
MIM: 607089
neXtProt: NX_O95273
Antibodypedia: O95273 (may not find the protein thus also not any antibody)
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