CCNY_HUMAN

Source: PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CCNY , C10orf9, CBCP1, CFP1
Protein names and data: CCNY_HUMAN , Cyclin-Y; Cyc-Y , Cyclin box protein 1; Cyclin fold protein 1; cyclin-X Lenght: 341 a.a.
Mass: 39337 Da
fasta formatted sequence
Function: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Isoform 3: Nucleus.
Tissue specificity: Widely expressed.

Database cross-references

UniProt: Q8ND76
Ensembl: ENST00000265375
Ensembl: ENST00000339497
Ensembl: ENST00000374704
Ensembl: ENST00000374706
MIM: 612786
neXtProt: NX_Q8ND76
Antibodypedia: Q8ND76 (may not find the protein thus also not any antibody)
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