CD63_HUMAN

Source: BSc_CH
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: CD63 , MLA1, TSPAN30
Protein names and data: CD63_HUMAN , CD63 antigen , Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD63 Lenght: 238 a.a.
Mass: 25637 Da
fasta formatted sequence
Function: This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation.
Cellular location: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Also found in Weibel- Palade bodies of endothelial cells. Located in platelet dense granules.
Tissue specificity: Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.

Database cross-references

UniProt: P08962
Ensembl: ENST00000257857
Ensembl: ENST00000546939
Ensembl: ENST00000549117
Ensembl: ENST00000550776
Ensembl: ENST00000552692
Ensembl: ENST00000552754
MIM: 155740
neXtProt: NX_P08962
Antibodypedia: P08962 (may not find the protein thus also not any antibody)
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