CKAP5_HUMAN

Source: PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: CKAP5 , KIAA0097
Protein names and data: CKAP5_HUMAN , Cytoskeleton-associated protein 5 , Colonic and hepatic tumor overexpressed gene protein; Ch-TOG Lenght: 2032 a.a.
Mass: 225495 Da
fasta formatted sequence
Function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles.
Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Detected on centrosomes during interphase. Detected on spindle poles and microtubules during mitosis.
Tissue specificity: Overexpressed in hepatomas and colonic tumors. Also expressed in skeletal muscle, brain, heart, placenta, lung, liver, kidney and pancreas.

Genetic variants

Database cross-references

UniProt: Q14008
Ensembl: ENST00000312055
Ensembl: ENST00000354558
Ensembl: ENST00000415402
Ensembl: ENST00000529230
MIM: 611142
neXtProt: NX_Q14008
Antibodypedia: Q14008 (may not find the protein thus also not any antibody)
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