CMBL_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CMBL
Protein names and data: CMBL_HUMAN , Carboxymethylenebutenolidase homolog; 3.1.-.- Lenght: 245 a.a.
Mass: 28048 Da
fasta formatted sequence
Function: Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
Cellular location: Cytoplasm, cytosol.
Tissue specificity: Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).

Genetic variants

Database cross-references

UniProt: Q96DG6
Ensembl: ENST00000296658
MIM: 613379
neXtProt: NX_Q96DG6
Antibodypedia: Q96DG6 (may not find the protein thus also not any antibody)
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