CNDP2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: CNDP2 , CN2, CPGL, PEPA
Protein names and data: CNDP2_HUMAN , Cytosolic non-specific dipeptidase; 3.4.13.18 , CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A Lenght: 475 a.a.
Mass: 52878 Da
fasta formatted sequence

Function: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.
Catalytic activity: Hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids.
Cellular location: Cytoplasm.
Tissue specificity: Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues.

Genetic variants

Database cross-references

UniProt: Q96KP4
Ensembl: ENST00000324262
Ensembl: ENST00000324301
Ensembl: ENST00000579847
MIM: 169800
neXtProt: NX_Q96KP4
Antibodypedia: Q96KP4 (may not find the protein thus also not any antibody)
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