Source: hRBCD ; ID: IPI00032038
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: CPT1A , CPT1
Protein names and data: CPT1A_HUMAN , Carnitine O-palmitoyltransferase 1, liver isoform; CPT1-L; , Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A Lenght: 773 a.a.
Mass: 88368 Da
fasta formatted sequence

Function: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.
Catalytic activity: Palmitoyl-CoA + L-carnitine = CoA + L- palmitoylcarnitine.
Pathway: Lipid metabolism; fatty acid beta-oxidation.
Cellular location: Mitochondrion outer membrane; Multi-pass membrane protein.
Tissue specificity: Strong expression in kidney and heart, and lower in liver and skeletal muscle.

Genetic variants

Database cross-references

UniProt: P50416
Ensembl: ENST00000265641
Ensembl: ENST00000376618
Ensembl: ENST00000539743
Ensembl: ENST00000540367
MIM: 255120
MIM: 600528
neXtProt: NX_P50416
Antibodypedia: P50416 (may not find the protein thus also not any antibody)
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