Source: BD_CD
Marked as 'Integral membrane protein'
Confidence: high (a blood group or CD marker) Search PubMed for
(RBC AND this entry)

Gene names: CSF3R , GCSFR
Protein names and data: CSF3R_HUMAN , Granulocyte colony-stimulating factor receptor; G-CSF receptor; G-CSF-R , CD114; Flags: Precursor Lenght: 836 a.a.
Mass: 92156 Da
fasta formatted sequence

Function: Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Cellular location: Isoform 2: Secreted (Probable). Cell membrane; Single-pass type I membrane protein.
Tissue specificity: One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.

Genetic variants

Database cross-references

UniProt: Q99062
Ensembl: ENST00000331941
Ensembl: ENST00000361632
Ensembl: ENST00000373103
Ensembl: ENST00000373104
Ensembl: ENST00000373106
Ensembl: ENST00000418048
Ensembl: ENST00000440588
MIM: 138971
MIM: 162830
neXtProt: NX_Q99062
Antibodypedia: Q99062 (may not find the protein thus also not any antibody)
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