DAAM1_HUMAN

Source: hRBCD ; ID: IPI00337800
PM19886704
PM23856902
BSc_CH
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: DAAM1 , KIAA0666
Protein names and data: DAAM1_HUMAN , Disheveled-associated activator of morphogenesis 1 Lenght: 1078 a.a.
Mass: 123473 Da
fasta formatted sequence
Function: Binds to disheveled (Dvl) and Rho, and mediates Wnt- induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments.
Cellular location: Cytoplasm. Note=Perinuclear.
Tissue specificity: Expressed in all tissues examined.

Database cross-references

UniProt: Q9Y4D1
Ensembl: ENST00000351081
Ensembl: ENST00000360909
Ensembl: ENST00000395125
MIM: 606626
neXtProt: NX_Q9Y4D1
Antibodypedia: Q9Y4D1 (may not find the protein thus also not any antibody)
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