DC1I1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: DYNC1I1 , DNCI1, DNCIC1
Protein names and data: DC1I1_HUMAN , Cytoplasmic dynein 1 intermediate chain 1 , Cytoplasmic dynein intermediate chain 1; Dynein intermediate chain 1, cytosolic; DH IC-1 Lenght: 645 a.a.
Mass: 72955 Da
fasta formatted sequence
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Cellular location: Cytoplasm (By similarity). Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.

Genetic variants

Database cross-references

UniProt: O14576
Ensembl: ENST00000324972
Ensembl: ENST00000359388
Ensembl: ENST00000447467
Ensembl: ENST00000457059
MIM: 603772
neXtProt: NX_O14576
Antibodypedia: O14576 (may not find the protein thus also not any antibody)
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