DCTN3_HUMAN

Source: PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: DCTN3 , DCTN22
Protein names and data: DCTN3_HUMAN , Dynactin subunit 3 , Dynactin complex subunit 22 kDa subunit; p22 Lenght: 186 a.a.
Mass: 21119 Da
fasta formatted sequence
Function: Together with dynein may be involved in spindle assembly and cytokinesis.
Cellular location: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
Tissue specificity: Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.

Database cross-references

UniProt: O75935
Ensembl: ENST00000259632
Ensembl: ENST00000341694
Ensembl: ENST00000378916
MIM: 607387
neXtProt: NX_O75935
Antibodypedia: O75935 (may not find the protein thus also not any antibody)
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