DEF1_HUMAN

Source: PM23856902
BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: DEFA1 , DEF1, DEFA2, MRS
Protein names and data: DEF1_HUMAN , Neutrophil defensin 1 , Defensin, alpha 1; HNP-1; HP-1; HP1; HP 1-56; Neutrophil defensin 2; HNP-2; HP-2; HP2; Flags: Precursor Lenght: 94 a.a.
Mass: 10201 Da
fasta formatted sequence

Function: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
Cellular location: Secreted.

Database cross-references

UniProt: P59665
Ensembl: ENST00000382679
Ensembl: ENST00000382689
Ensembl: ENST00000382692
Ensembl: ENST00000535841
MIM: 125220
neXtProt: NX_P59665
Antibodypedia: P59665 (may not find the protein thus also not any antibody)
Local full text data: click here

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