DEN1A_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: DENND1A , FAM31A, KIAA1608
Protein names and data: DEN1A_HUMAN , DENN domain-containing protein 1A , Connecdenn 1; Connecdenn; Protein FAM31A Lenght: 1009 a.a.
Mass: 110577 Da
fasta formatted sequence
Function: Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles.
Cellular location: Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane.

Database cross-references

UniProt: Q8TEH3
Ensembl: ENST00000373618
Ensembl: ENST00000373620
Ensembl: ENST00000373624
Ensembl: ENST00000394215
Ensembl: ENST00000394219
Ensembl: ENST00000542603
MIM: 613633
neXtProt: NX_Q8TEH3
Antibodypedia: Q8TEH3 (may not find the protein thus also not any antibody)
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