DHE3_HUMAN

Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: GLUD1 , GLUD
Protein names and data: DHE3_HUMAN , Glutamate dehydrogenase 1, mitochondrial; GDH 1; 1.4.1.3; Flags: Precursor Lenght: 558 a.a.
Mass: 61398 Da
fasta formatted sequence

Function: Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
Catalytic activity: L-glutamate + H(2)O + NAD(P)(+) = 2- oxoglutarate + NH(3) + NAD(P)H.
Disease:
Cellular location: Mitochondrion matrix.

Genetic variants

Database cross-references

UniProt: P00367
Ensembl: ENST00000277865
MIM: 138130
MIM: 606762
neXtProt: NX_P00367
Antibodypedia: P00367 (may not find the protein thus also not any antibody)
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