DJB11_HUMAN

Source: PM23856902
BSc_CH
PM22954596
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: DNAJB11 , EDJ, ERJ3, HDJ9 , PSEC0121, UNQ537/PRO1080
Protein names and data: DJB11_HUMAN , DnaJ homolog subfamily B member 11 , APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4; Flags: Precursor Lenght: 358 a.a.
Mass: 40514 Da
fasta formatted sequence
Function: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.
Cellular location: Endoplasmic reticulum lumen. Note=Associated with the ER membrane in a C-terminally epitope-tagged construct.
Tissue specificity: Widely expressed.

Genetic variants

Database cross-references

UniProt: Q9UBS4
Ensembl: ENST00000265028
Ensembl: ENST00000439351
MIM: 611341
neXtProt: NX_Q9UBS4
Antibodypedia: Q9UBS4 (may not find the protein thus also not any antibody)
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