DNPH1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: DNPH1 , C6orf108, RCL
Protein names and data: DNPH1_HUMAN , 2'-deoxynucleoside 5'-phosphate N-hydrolase 1; 3.2.2.- , c-Myc-responsive protein RCL Lenght: 174 a.a.
Mass: 19108 Da
fasta formatted sequence
Function: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'- monophosphates containing purine bases are preferred to those containing pyrimidine bases (By similarity).
Catalytic activity: A deoxyribonucleoside 5'-monophosphate + H(2)0 = deoxyribose 5-monophosphate + a purine or pyrimidine base.
Cellular location: Cytoplasm. Nucleus (By similarity).
Tissue specificity: Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers.

Database cross-references

UniProt: O43598
Ensembl: ENST00000230431
Ensembl: ENST00000393987
neXtProt: NX_O43598
Antibodypedia: O43598 (may not find the protein thus also not any antibody)
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