DOHH_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: DOHH , HLRC1
Protein names and data: DOHH_HUMAN , Deoxyhypusine hydroxylase; hDOHH; 1.14.99.29 , Deoxyhypusine dioxygenase; Deoxyhypusine monooxygenase; HEAT-like repeat-containing protein 1 Lenght: 302 a.a.
Mass: 32904 Da
fasta formatted sequence

Function: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)- L-lysine intermediate to form hypusine, an essential post- translational modification only found in mature eIF-5A factor.
Catalytic activity: [eIF5A]-deoxyhypusine + AH(2) + O(2) = [eIF5A]-hypusine + A + H(2)O.
Pathway: Protein modification; eIF5A hypusination.

Database cross-references

UniProt: Q9BU89
Ensembl: ENST00000250937
Ensembl: ENST00000427575
MIM: 611262
neXtProt: NX_Q9BU89
Antibodypedia: Q9BU89 (may not find the protein thus also not any antibody)
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