DSC1_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: DSC1 , CDHF1
Protein names and data: DSC1_HUMAN , Desmocollin-1 , Cadherin family member 1; Desmosomal glycoprotein 2/3; DG2/DG3; Flags: Precursor Lenght: 894 a.a.
Mass: 99987 Da
fasta formatted sequence
Function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues.
Cellular location: Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Tissue specificity: Strongly expressed in epidermis, less in lymph node and tongue.

Genetic variants

Database cross-references

UniProt: Q08554
Ensembl: ENST00000257197
Ensembl: ENST00000257198
MIM: 125643
neXtProt: NX_Q08554
Antibodypedia: Q08554 (may not find the protein thus also not any antibody)
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