DSCL1_HUMAN

Source: hRBCD ; ID: IPI00154755
PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: DSCAML1 , DSCAM2, KIAA1132
Protein names and data: DSCL1_HUMAN , Down syndrome cell adhesion molecule-like protein 1 , Down syndrome cell adhesion molecule 2; Flags: Precursor Lenght: 2053 a.a.
Mass: 224463 Da
fasta formatted sequence
Function: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells (By similarity).
Cellular location: Cell membrane; Single-pass type I membrane protein (Potential).
Tissue specificity: Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus.

Genetic variants

Database cross-references

UniProt: Q8TD84
Ensembl: ENST00000321322
MIM: 611782
neXtProt: NX_Q8TD84
Antibodypedia: Q8TD84 (may not find the protein thus also not any antibody)
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