DUS23_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: DUSP23 , LDP3, VHZ
Protein names and data: DUS23_HUMAN , Dual specificity protein phosphatase 23; 3.1.3.16; 3.1.3.48 , Low molecular mass dual specificity phosphatase 3; LDP-3; VH1-like phosphatase Z Lenght: 150 a.a.
Mass: 16588 Da
fasta formatted sequence
Function: Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. A phosphoprotein + H(2)O = a protein + phosphate.
Cellular location: Cytoplasm, cytosol. Nucleus. Note=Mainly cytosolic. Also nuclear.
Tissue specificity: Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.

Genetic variants

Database cross-references

UniProt: Q9BVJ7
Ensembl: ENST00000368107
Ensembl: ENST00000368108
Ensembl: ENST00000368109
neXtProt: NX_Q9BVJ7
Antibodypedia: Q9BVJ7 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.