EIF3I_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: EIF3I , EIF3S2, TRIP1
Protein names and data: EIF3I_HUMAN , Eukaryotic translation initiation factor 3 subunit I; eIF3i , Eukaryotic translation initiation factor 3 subunit 2; TGF-beta receptor-interacting protein 1; TRIP-1; eIF-3-beta; eIF3 p36 Lenght: 325 a.a.
Mass: 36502 Da
fasta formatted sequence
Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Cellular location: Cytoplasm (By similarity).

Database cross-references

UniProt: Q13347
Ensembl: ENST00000373586
MIM: 603911
neXtProt: NX_Q13347
Antibodypedia: Q13347 (may not find the protein thus also not any antibody)
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