Source: PM19886704
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: ELANE , ELA2
Protein names and data: ELNE_HUMAN , Neutrophil elastase; , Bone marrow serine protease; Elastase-2; Human leukocyte elastase; HLE; Medullasin; PMN elastase; Flags: Precursor Lenght: 267 a.a.
Mass: 28518 Da
fasta formatted sequence

Function: Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis.
Catalytic activity: Hydrolysis of proteins, including elastin. Preferential cleavage: Val-|-Xaa > Ala-|-Xaa.
Tissue specificity: Bone marrow cells.

Genetic variants

Database cross-references

UniProt: P08246
Ensembl: ENST00000263621
Ensembl: ENST00000590230
MIM: 130130
MIM: 162800
MIM: 202700
neXtProt: NX_P08246
Antibodypedia: P08246 (may not find the protein thus also not any antibody)
Local full text data: click here

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