EM55_HUMAN

Source: hRBCD ; ID: IPI00215610
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: MPP1 , DXS552E, EMP55
Protein names and data: EM55_HUMAN , 55 kDa erythrocyte membrane protein; p55 , Membrane protein, palmitoylated 1 Lenght: 466 a.a.
Mass: 52296 Da
fasta formatted sequence
Function: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
Cellular location: Membrane; Lipid-anchor. Cell projection, stereocilium (By similarity). Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non- myelin-forming Schwann cells.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: Q00013
Ensembl: ENST00000369534
Ensembl: ENST00000393531
Ensembl: ENST00000413259
Ensembl: ENST00000595966
Ensembl: ENST00000597401
Ensembl: ENST00000599769
MIM: 305360
neXtProt: NX_Q00013
Antibodypedia: Q00013 (may not find the protein thus also not any antibody)
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