ENOPH_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ENOPH1 , MASA , MSTP145
Protein names and data: ENOPH_HUMAN , Enolase-phosphatase E1; 3.1.3.77 , 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; MASA homolog Lenght: 261 a.a.
Mass: 28933 Da
fasta formatted sequence
Function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene).
Catalytic activity: 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
Pathway: Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6. Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.
Cellular location: Cytoplasm (By similarity). Nucleus (By similarity).

Database cross-references

UniProt: Q9UHY7
Ensembl: ENST00000273920
Ensembl: ENST00000505846
neXtProt: NX_Q9UHY7
Antibodypedia: Q9UHY7 (may not find the protein thus also not any antibody)
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