Source: PM19886704
Marked as 'Membrane associated protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: EPS15L1 , EPS15R
Protein names and data: EP15R_HUMAN , Epidermal growth factor receptor substrate 15-like 1 , Eps15-related protein; Eps15R Lenght: 864 a.a.
Mass: 94255 Da
fasta formatted sequence

Function: Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Cellular location: Cell membrane; Peripheral membrane protein (By similarity). Nucleus (By similarity). Membrane, coated pit (By similarity). Note=Localized to plasma membrane coated pits (By similarity).

Database cross-references

UniProt: Q9UBC2
Ensembl: ENST00000248070
Ensembl: ENST00000455140
Ensembl: ENST00000535753
Ensembl: ENST00000597937
Ensembl: ENST00000602022
neXtProt: NX_Q9UBC2
Antibodypedia: Q9UBC2 (may not find the protein thus also not any antibody)
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