EPN4_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: CLINT1 , ENTH, EPN4, EPNR, KIAA0171
Protein names and data: EPN4_HUMAN , Clathrin interactor 1 , Clathrin-interacting protein localized in the trans-Golgi region; Clint; Enthoprotin; Epsin-4; Epsin-related protein; EpsinR Lenght: 625 a.a.
Mass: 68259 Da
fasta formatted sequence

Function: Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.
Cellular location: Cytoplasm. Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
Tissue specificity: Ubiquitously expressed at low to intermediate levels.

Database cross-references

UniProt: Q14677
Ensembl: ENST00000296951
Ensembl: ENST00000411809
Ensembl: ENST00000523094
Ensembl: ENST00000523908
Ensembl: ENST00000530742
MIM: 607265
neXtProt: NX_Q14677
Antibodypedia: Q14677 (may not find the protein thus also not any antibody)
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