ERD21_HUMAN

Source: PM23856902
PM22954596
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: KDELR1 , ERD2.1
Protein names and data: ERD21_HUMAN , ER lumen protein retaining receptor 1 , KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; Putative MAPK-activating protein PM23 Lenght: 212 a.a.
Mass: 24542 Da
fasta formatted sequence
Function: Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi.
Cellular location: Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane.

Database cross-references

UniProt: P24390
Ensembl: ENST00000330720
MIM: 131235
neXtProt: NX_P24390
Antibodypedia: P24390 (may not find the protein thus also not any antibody)
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