ERF3A_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: GSPT1 , ERF3A
Protein names and data: ERF3A_HUMAN , Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; eRF3a , G1 to S phase transition protein 1 homolog Lenght: 499 a.a.
Mass: 55756 Da
fasta formatted sequence
Function: Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Database cross-references

UniProt: P15170
Ensembl: ENST00000420576
Ensembl: ENST00000434724
Ensembl: ENST00000439887
Ensembl: ENST00000563468
MIM: 139259
neXtProt: NX_P15170
Antibodypedia: P15170 (may not find the protein thus also not any antibody)
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