Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: ERLIN2 , C8orf2, SPFH2 , UNQ2441/PRO5003/PRO9924
Protein names and data: ERLN2_HUMAN , Erlin-2 , Endoplasmic reticulum lipid raft-associated protein 2; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; SPFH domain-containing protein 2 Lenght: 339 a.a.
Mass: 37840 Da
fasta formatted sequence

Function: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway.
Cellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: O94905
Ensembl: ENST00000276461
Ensembl: ENST00000335171
Ensembl: ENST00000397228
Ensembl: ENST00000518586
Ensembl: ENST00000519638
Ensembl: ENST00000523107
Ensembl: ENST00000523887
MIM: 611225
MIM: 611605
neXtProt: NX_O94905
Antibodypedia: O94905 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.