ERP44_HUMAN

Source: PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: ERP44 , KIAA0573, TXNDC4 , UNQ532/PRO1075
Protein names and data: ERP44_HUMAN , Endoplasmic reticulum resident protein 44; ER protein 44; ERp44 , Thioredoxin domain-containing protein 4; Flags: Precursor Lenght: 406 a.a.
Mass: 46971 Da
fasta formatted sequence
Function: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Cellular location: Endoplasmic reticulum lumen.

Database cross-references

UniProt: Q9BS26
Ensembl: ENST00000262455
MIM: 609170
neXtProt: NX_Q9BS26
Antibodypedia: Q9BS26 (may not find the protein thus also not any antibody)
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