FCG3A_HUMAN

Source: PM19886704
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: FCGR3A , CD16A, FCG3, FCGR3, IGFR3
Protein names and data: FCG3A_HUMAN , Low affinity immunoglobulin gamma Fc region receptor III-A , CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD16a; Flags: Precursor Lenght: 254 a.a.
Mass: 29089 Da
fasta formatted sequence
Function: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Cellular location: Cell membrane; Single-pass type I membrane protein (Potential). Secreted. Note=Exists also as a soluble receptor.
Tissue specificity: Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

Genetic variants

Database cross-references

UniProt: P08637
Ensembl: ENST00000367967
Ensembl: ENST00000436743
Ensembl: ENST00000540048
MIM: 146740
neXtProt: NX_P08637
Antibodypedia: P08637 (may not find the protein thus also not any antibody)
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