FCL_HUMAN

Source: hRBCD ; ID: IPI00014361
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: TSTA3 , SDR4E1
Protein names and data: FCL_HUMAN , GDP-L-fucose synthase; 1.1.1.271 , GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; Protein FX; Red cell NADP(H)-binding protein; Short-chain dehydrogenase/reductase family 4E member 1 Lenght: 321 a.a.
Mass: 35893 Da
fasta formatted sequence
Function: Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Catalytic activity: GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-6- deoxy-alpha-D-mannose + NADPH.
Pathway: Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.

Database cross-references

UniProt: Q13630
Ensembl: ENST00000425753
Ensembl: ENST00000529064
MIM: 137020
neXtProt: NX_Q13630
Antibodypedia: Q13630 (may not find the protein thus also not any antibody)
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