FCN2_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: FCN2 , FCNL
Protein names and data: FCN2_HUMAN , Ficolin-2 , 37 kDa elastin-binding protein; Collagen/fibrinogen domain-containing protein 2; EBP-37; Ficolin-B; Ficolin-beta; Hucolin; L-ficolin; Serum lectin p35; Flags: Precursor Lenght: 313 a.a.
Mass: 34001 Da
fasta formatted sequence
Function: May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
Cellular location: Secreted.
Tissue specificity: Expressed by the liver and secreted in plasma.

Genetic variants

Database cross-references

UniProt: Q15485
Ensembl: ENST00000291744
Ensembl: ENST00000350339
MIM: 601624
neXtProt: NX_Q15485
Antibodypedia: Q15485 (may not find the protein thus also not any antibody)
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