RBCC Red Blood Cell Collection

FETUA_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: AHSG , FETUA , PRO2743
Protein names and data: FETUA_HUMAN , Alpha-2-HS-glycoprotein , Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A; Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B; Flags: Precursor Lenght: 367 a.a.
Mass: 39325 Da
fasta formatted sequence
Function: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
Cellular location: Secreted.
Tissue specificity: Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

Genetic variants

There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256.

142 - 142 V -> L (in dbSNP:rs7633550). VAR_055802 7633550
248 - 248 T -> M (in allele AHSG*2; dbSNP:rs4917). VAR_002388 4917
256 - 256 T -> S (in allele AHSG*2; dbSNP:rs4918). VAR_002389 4918
276 - 276 D -> N (in allele AHSG*5; dbSNP:rs70961709). VAR_012474 70961709
317 - 317 R -> C (in allele AHSG*3; dbSNP:rs35457250). VAR_012475 35457250

Database cross-references

UniProt: P02765
Ensembl: ENST00000411641
MIM: 138680
neXtProt: NX_P02765
Antibodypedia: P02765 (may not find the protein thus also not any antibody)
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