FHOD1_HUMAN

Source: PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: FHOD1 , FHOS, FHOS1
Protein names and data: FHOD1_HUMAN , FH1/FH2 domain-containing protein 1 , Formin homolog overexpressed in spleen 1; FHOS; Formin homology 2 domain-containing protein 1 Lenght: 1164 a.a.
Mass: 126551 Da
fasta formatted sequence
Function: Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.
Cellular location: Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic.
Tissue specificity: Ubiquitous. Highly expressed in spleen.

Database cross-references

UniProt: Q9Y613
Ensembl: ENST00000258201
MIM: 606881
neXtProt: NX_Q9Y613
Antibodypedia: Q9Y613 (may not find the protein thus also not any antibody)
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