FIS1_HUMAN

Source: hRBCD ; ID: IPI00007052
PM19886704
PM23856902
PM22954596
Marked as 'Integral membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: FIS1 , TTC11 , CGI-135
Protein names and data: FIS1_HUMAN , Mitochondrial fission 1 protein , FIS1 homolog; hFis1; Tetratricopeptide repeat protein 11; TPR repeat protein 11 Lenght: 152 a.a.
Mass: 16938 Da
fasta formatted sequence
Function: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
Cellular location: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.

Database cross-references

UniProt: Q9Y3D6
Ensembl: ENST00000223136
MIM: 609003
neXtProt: NX_Q9Y3D6
Antibodypedia: Q9Y3D6 (may not find the protein thus also not any antibody)
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