FLOT2_HUMAN

Source: hRBCD ; ID: IPI00029625
PM19886704
PM23856902
PM22954596
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: FLOT2 , ESA1, M17S1
Protein names and data: FLOT2_HUMAN , Flotillin-2 , Epidermal surface antigen; ESA; Membrane component chromosome 17 surface marker 1 Lenght: 428 a.a.
Mass: 47064 Da
fasta formatted sequence
Function: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Cellular location: Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Note=Membrane-associated protein of caveolae.
Tissue specificity: In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.

Genetic variants

Database cross-references

UniProt: Q14254
Ensembl: ENST00000394908
MIM: 131560
neXtProt: NX_Q14254
Antibodypedia: Q14254 (may not find the protein thus also not any antibody)
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