RBCC Red Blood Cell Collection

FOCAD_HUMAN

Source: PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: FOCAD , KIAA1797
Protein names and data: FOCAD_HUMAN , Focadhesin Lenght: 1801 a.a.
Mass: 200072 Da
fasta formatted sequence
Function: Potential tumor suppressor in gliomas (By similarity).
Cellular location: Membrane; Multi-pass membrane protein (Potential). Cell junction, focal adhesion. Note=Colocalizes with VCL in astrocytes.
Tissue specificity: Ubiquitous. High expression in brain followed by testis, muscle, pancreas, heart, ovary, small intestine, placenta, prostate, thymus, kidney, colon, liver, lung, spleen and leukocytes. Expression is reduced in most glioblastomas and all glioblastoma cell lines.

Genetic variants

166 - 166 L -> S (in dbSNP:rs10511687). VAR_037877 10511687
234 - 234 V -> I (in dbSNP:rs10441706). VAR_037878 10441706
523 - 523 I -> V (in dbSNP:rs17832431). VAR_037879 17832431
718 - 718 T -> S (in dbSNP:rs7875872). VAR_037880 7875872
721 - 721 E -> K (in dbSNP:rs10964742). VAR_049528 10964742
1373 - 1373 T -> A (in dbSNP:rs3206852). VAR_061251 3206852
1373 - 1373 T -> P (in dbSNP:rs3206852). VAR_037881 3206852
1373 - 1373 T -> S (in dbSNP:rs3206852). VAR_061252 3206852
1668 - 1668 K -> E (in dbSNP:rs4977881). VAR_037882 4977881

Database cross-references

UniProt: Q5VW36
Ensembl: ENST00000338382
Ensembl: ENST00000380249
MIM: 614606
neXtProt: NX_Q5VW36
Antibodypedia: Q5VW36 (may not find the protein thus also not any antibody)
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